Bosses

For corresponding page on Binding of Isaac: Rebirth Wiki, see Bosses .

Bosses are strong monsters found in boss rooms at the end of a floor. The boss at the end of the floor must be defeated in order to advance to the next floor. The boss for a particular floor is chosen from the pool of bosses for the environment of the floor. Upon defeat, most bosses will drop an item from the boss item pool.

Bosses

Name	Portrait	Health	Description	ID.Variant.SubType	Location	Mod
The Peeping		550	Protected by some little buddies, the peeping uses a variety of blood barrages to attack isaac.	500.9900.0	N/A	The Peeping
Moira	150px	3000 +150	Fights using eyeballs.	777.0.0	N/A	The Ritual
PeePeeDie		2500 +200	An invulnerable boss with only one weak spot.	780.0.0	N/A	The Ritual
Puck	150px	500 +30	Fights with magic runes that change how the player fights.	608.0.10	N/A	Lunatic Mod
Souleater	150px	2000	Attacks the player using deadly blood lasers, and tricky projectile patterns.	800.125.0	N/A	Godmode: Unleashed
Serpent			Shoots the player along some platforms.	.1.1	N/A	Genesis+
Honeydrop		110	A queen bee who attacks using shockwaves and by spawning flies to fight for him.	67.3.0	N/A	Devil's Harvest
Technopin		100	An early boss that attacks by firing a laser towards isaac, and by leaping towards him.	62.0.10	N/A	Devil's Harvest
Cacamancer		300	A large boss that fights by summoning poopy friends.	699.0.0	N/A	Devil's Harvest
Mega Blister		300	A large blister that summons not one, not three, but TWO little balls as part of their attack!	303.0.5	N/A	Devil's Harvest
Mega Portal		200 +5	A big portal that summons other bosses to fight for them.	697.0.0	N/A	Devil's Harvest
Primordial Monstro	150px	250	This old Monstro protect himself with Ministros.	20.415.0	N/A	Devil's Harvest
Mahalath		477	A demonic boss that fights using their vomit.	777.0.0	N/A	Devil's Harvest